Delta-8, Delta-9, Delta-10 – What Is the Difference?

Delta-8, Delta-9, and Delta-10…it’s a lot of deltas. Many users of cannabis alive today can easily remember a time when tetrahydrocannabinol (THC, the main psychoactive substance) was just THC. The cannabinoid is well-known for having the primary psychoactive properties found in marijuana and, in trace amounts, hemp plants, but that was the end of the story.

More recently, an increase in rigorous scientific experimentation has uncovered some interesting other compounds. It turns out, not all THC is created equal. Now, chemists and serious cannabis enthusiasts alike are talking about various delta varieties of THC and how they could provide more targeted beneficial effects and potential benefits for the human body.

The three best-known THC variants are Delta-8, Delta-9, and Delta-10. People looking for new cannabinoid products to try often find themselves confused by the differences between these three extracts, but they don’t need to get frustrated or overwhelmed. Instead, read on to find out about the key differences, chemical structures, and other factors between Delta-8, Delta-9, and Delta-10 THC before purchasing that next product.

Understanding the basics

Before discussing the main difference and varying strength levels and effects of these three popular forms of THC, let’s take a moment to discuss the name changes. To chemists, it’s all pretty straightforward. THC is the base chemical structure. Additional molecules can be added, removed, or rearranged from it to create chemical compounds known as unique isomers, in this case, Delta-8, -9, and -10 (1). Delta 8 THC and Delta 10 THC are technically legal federally due to the fact that they have less than .3% Delta 9 THC in their overall weight. Because of this, users who are outside of medical marijuana states are turning to these cannabinoids for their possible benefits such as pain relief.

Although they are federally legal, they are not regulated by the FDA. It’s important to buy from a reputable source, as there are always safety concerns in unregulated markets. Unclean products can cause negative side effects, so choosing companies like Earthy Select who have Certificate of Analysis for every product is extremely important.

Since these THC isomers share the same base structure, they tend to affect people in very similar ways. Each of them follows the same metabolic pathways to arrive at the body’s endocannabinoid receptors, where all the unique isomers still bind to CB1 receptors. There are, however, some differences in how the structure of each THC isomer interacts with the CB1 receptors, so while the effects of all the delta iterations are similar, they’re not identical.

All of these isomers interact differently with cannabinoid receptors similarly and differently than traditional cannabis. The way cannabinoids interact with cannabinoid receptors through the Endocannabinoid system determine how the nervous system reacts and produce different properties like a euphoric high, energizing effects, or other forms of what we’d refer to as a high feeling.

Delta-8 in detail

Now that cannabis users understand the basics of how the three isomers are formed, it’s time to take a look at how they stack up. Most people view the Delta-8 compound as one of the calmer THC isomers. It is usually derived from hemp instead of marijuana, and its effects closely resemble a milder version of those associated with Indica cannabis strains.

Though some people view Delta-8 THC as being more like CBD, it does have some of the psychoactive effects of Delta-9 THC, the stronger of the isomers more commonly found in high concentrations in recreational marijuana. The psychoactive effects are, however, less pronounced and potential benefits differ from Delta 10 THC and Delta 9 THC.

Delta 8 THC contributes to the entourage effect without inducing a full-blown psychoactive experience, allowing users to get the benefits of THC while maintaining a clear-headedness not typically associated with more potent THC products (2). Delta-8 is also more stable than Delta-9, meaning that it won’t degrade as readily into CBN. It’s also legal in most states, even those that do not have provisions for medical or recreational marijuana.

Delta-9 in detail

The Delta-9 THC isomer is what most people think of as “regular” THC. It creates far more potent psychoactive effects (although not a higher potency, it has the potential to feel like high potency products because it’s generally stronger than Delta 8 THC and Delta 10 THC) and is more often extracted from marijuana than hemp (3). As a result, Delta-9 THC is only legal in states that have legalized marijuana for medical or recreational use.

The effects of Delta-9 THC are more variable than those of the Delta-8 isomer. They are strongly impacted by the mix of other cannabinoids and terpenes found in the strain, that can have a compound effect. For instance, an indica strain may have more sedative effects due to its terpene content, where as sativa strains may have more euphoric effects due to its variety of terpenes. It can be harder for first time users to predict their responses to Delta-9 THC.

Delta-9 THC is also responsible for most of the reported side effects of marijuana use, including anxiety, paranoia, and the infamous munchies. It also creates stronger cognitive impairments, which can be a problem for those who use cannabis products to support wellness in their daily lives.

Delta-10 in detail

While cannabis manufacturers and many consumers have been aware of the delta-8 isomer for several years, delta-10 is a newcomer on the scene (4). It occurs only in minute amounts, which means it can’t be extracted as easily as delta-8 or delta-9 variations.

Like Delta-8 THC, the Delta-10 isomer is extracted from hemp, not marijuana. As a result, it’s legal in most states, though it can lead to failed drug tests since most tests can’t differentiate between the different THC isomers. Effects-wise, though, the two isomers are quite different.

The effects of Delta-10 THC are said to be more euphoric effects, uplifting and less calming than those of the Delta-8 isomer. For those used to the more “traditional” Delta-9 variation of THC, some of the effects of Delta-10 will feel familiar, if more subtle. It can induce a state of increased creativity, energy, and focus but doesn’t come with the paranoia or spaciness associated with Delta-9 THC.

Earthy Now High CBD Low THC Cannabis CBD Pre-Rolls

Know your THC: Delta-8, Delta-9, Delta-10 isomers

Since researchers and manufacturers have only recently begun to isolate different isomers of THC, most people aren’t very familiar with what they are or how they work. Cannabis enthusiasts who want to learn a little more about Delta-8, -9, and -10 isomers can read on to find answers to some of consumers’ most frequently asked questions.

Are these newly discovered Delta-8 & Delta-10 isomers safe?

Since all three THC isomers are so close in structure, the body responds to them in similar ways. All three forms of THC are generally tolerated well by most people, especially in small doses. While they are generally considered safe, it’s important for consumers to purchase extracts only from reputable vendors willing to release certificates of analysis (COAs) for all of their products.

What is a COA?

certificate of analysis (COA) is a document attesting to a product’s laboratory analysis for cannabinoids and in some cases adulterants, heavy metals and pesticides. It is a useful tool for cannabis producers and customers to ensure quality and trust.

Will Delta-8, Delta-9, Delta-10 THC isomers show up on drug tests?

Though modern drug tests are designed to look for signs of Delta-9 THC, they cannot distinguish between the different isomers. Even Delta-8 or Delta-10 extracts derived from hemp can still cause users to fail drug screening. Please note that full spectrum CBD products can potentially cause a failed test for THC as well.

Are the Delta-8, Delta-9, Delta-10 THC isomers legal?

In states with legal medical or recreational marijuana, many forms of THC are legal to buy, possess, and consume. Delta-8 and Delta-10 are also legal in most states where marijuana products remain illegal, with a few exceptions.

Delta-8, Delta-9, Delta-10 final thoughts

There has never been a better time to start using cannabis. The proliferation of different extracts, including THC variations, gives consumers more control than ever over what kinds of experiences they will have when using hemp and marijuana products. Feel free to experiment within the bounds of legality, but make sure to buy extracts only from reputable vendors like Earthy Select.

Disclaimer – Information is provided for educational purposes. It does not, and is not intended to, constitute legal advice or medical advice. We attempt to be accurate and up to date but the legality of cannabinoids and the science of cannabis is evolving. The author is neither a lawyer or a legal expert, nor a doctor or medical expert. You should check with your local authorities and medical providers before buying or using any products.


  1. Molecular Targets of the Phytocannabinoids-A Complex Picture
  2. Taming THC: Potential Cannabis Synergy and Phytocannabinoid-terpenoid Entourage Effects
  3. Potency of Delta-9 THC and Other Cannabinoids in Cannabis In England in 2005
  4. Delta-10 THC Infinitecal ACS Laboratory

Earthy Select Delta-8 Delta-10 Full spectrum oils

Frequently Asked Questions

There is a risk of failing a drug test. It depends on the type of CBD product one is using.

Drug tests for marijuana generally identify THC or its metabolites. Although tests do not screen for CBD, full spectrum CBD products contain low quantities of THC that can make a person fail a drug test. If you anticipate taking a drug test, we suggest checking with your employer or test administrator for clarity prior to taking full spectrum CBD products.

Yes, but even though these products are federally-compliant, individual states may have their own regulations about purchasing or using hemp-based products, and these are subject to change. You should check your state and local rules before ordering. We ship nationwide.

Hemp-derived means made from hemp, sometimes also referred to as industrial hemp. The 2018 Farm Bill (see next section) established new federal legal definitions and rules for hemp, including that hemp and “and any part of that plant, including the seeds thereof and all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers, whether growing or not, with a delta-9 tetrahydrocannabinol concentration of not more than 0.3 percent on a dry weight basis” may be used for production, sales, transport, and use.